Reprogramming Recovery

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Benchmarking methods for transcription factor prioritization.

View the Project on GitHub gifford-lab/ReprogrammingRecovery

Consensus Mouse Motif Database

We generated and hand-annotated a consensus motif database of 107 mouse transcription factor groups by clustering the HOCOMOCOv11 mouse database of 356 transcription factor motifs.

The script to compute similarity and perform affinity propagation clustering of the motifs is available here.

We provide this database in the following formats:

  1. MEME
  2. Chan format PCM

We also provide a mapping from consensus motif to transcription factor motifs within the cluster. Stars denote the transcription factor motif within the group that is used as the representative motif for the cluster.